CAS No.:: 19099-93-5Molecular Formula: C13H15NO3
1-benzyloxycarbonyl-piperidin-4-one
1-carbobenzyloxy-4-piperidone
1-Cbz-4-piperidinone
Benzyl 4-oxo-1-piperidinecarboxylate
1-Piperidinecarboxylic acid, 4-oxo-, phenylmethyl ester
1-(Benzyloxycarbonyl)-4-piperidinone
1-Z-4-Piperidone
4-Oxo-1-piperidinecarboxylic Acid Benzyl Ester
1-Cbz-4-piperidone
benzyl 4-oxopiperidine-1-carboxylate
1-Cbz-piperidin-4-one
1-Benzyloxycarbonyl-4-piperidine
N-CBZ-4-piperidone
1-Carbobenzoxy-4-piperidone
4-oxo-piperidine-1-carboxylic acid benzyl ester
MFCD00673144
Chemical Properties
Colourless Oil
Uses
Protected piperidinone that can undergo interesting synthetic transformations including the Knoevenagel reaction,1 hetero-Diels-Alder reactions,2 and reactions to form N-(4-piperidinyl)oxindoles.
General Description
1-Z-4-Piperidone is the starting material in biheteroaromatic diphosphine oxides-catalyzed stereoselective direct aldol condensation reactions.
Protective piperidone can be used for synthesis and transformation reactions that have attracted much attention, including Knoevenagel reaction, heterogeneous Diels-Alder reaction, and the formation of N-(4-piperidyl) hydroxyindole. The raw material for synthesis of GABA analogues by direct Barbier- type addition reaction of alkyl phosphonate.
Product Name | 1-(Benzyloxycarbonyl)-4-piperidinone |
CAS NO. | 19099-93-5 |
EINECS | 606-227-7 |
Meltling Point | 38-41°C |
Boiling Point | 384.1±42.0 °C at 760 mmHg |
Flashing Point | 186.1±27.9 °C |
Molecular Formula | C13H15NO3 |
Molecular Weight | 233.263 |
Purity | 99% |
Density | 1.2±0.1 g/cm3 |
PSA | 46.61 |
LogP | 1 |
Refractive Index | 1.56 |
Vapour pressure | 0.0±0.9 mmHg at 25°C |
Appearance | White crystalline powder / White to pale yellow Solid or Lliquid |
HS Code | 2933399090 |
Shelf Life: | 2years |
Storage | Sealed in dry,2-8°C |
Stability | stable at room temperature and pressure Materials to Avoid: Oxides |
Solubility | Chloroform, Dichloromethane, Ethyl Acetate, Methanol |