Product Detail

99% High Quality Original Powder Lumefantrine CAS82186-77-4 with Safe Delivery

Basic Information

What is Febuxostat?

Benflumetol, a novel antimalarial compound belonging to the fluorenes (2,3-benzindenes), has high blood schizontocidal activity, in vitro and in vivo, against mammalian plasmodia, including chloroquine-resistant Plasmodium falciparum. Due to its molecular structure benflumetol occurs in the dextrorotatory and the laevorotatory form. Normal synthesis yields the racemate of both enantiomers. Enantiomers of some antimalarial drugs possess different specific activity. It was therefore of interest to compare the response of P. falciparum to the enantiomers and the racemate of benflumetol in a variety of fresh, natural isolates. Measuring the concentration-specific inhibition of schizont maturation, the parallel investigation of 29 isolates produced no evidence of substantial activity differences between (+)-benflumetol, (−)-benflumetol and racemic benflumetol, the mean EC-50 values being 8.87, 9.71 and 12.44 nmol/l blood-medium-mixture, respectively.

Lumefantrine (benflumetol) is created for the drug of mefloquine on Plasmodium vivax sexual and asexual body a clear killing effect on P. vivax has a good effect to prevent.

Function   
It is mainly used for the treatment of cerebral malaria (malarial malaria), especially for the treatment of cerebral malaria (palatal malaria) caused by chloroquine-resistant strains.

Application
Antimalarial drug.
Lumefantrine (Benflumetol) is a new kinds of mefloquine drug.
Obvious Effect of killing vivax malaria, as well as in preventing.
It also can kill the Falciparum malaria phorozoon, but slow effect.
It can reduce the gametophyte rate in blood, suppression the development of the gametophyte in mosquitoes.
The cure rate of chloroquine-resistant and multidrug-resistant falciparum malaria is more than 95%.
It will be more effect when used in conjunction with the Artemether.
Animal experiments show that the toxicity of this product is very low, and no adverse reaction on the clinical.