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Biocar Pharmaceutical Co.,Ltd. 2021 Registered
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99% High Quality Original Powder Memantine CAS 19982-08-2 with Safe Delivery Inquiries(0) Tags:Memantine CAS 19982-08-2 Price: US $1.201-1000 Quantity: piece Total price:US $0.00 (Excluding shipping cost) Add to Inquiry Cart Add to Wish List (0 Adds) Ship From: Hongkong Support Payment Terms: T/T,L/C Biocar Pharmaceutical Co.,Ltd. 2021 Registered

Hubei, China. This supplier has been open since 2004

Business Type: SOHO/Individual Main Products: Samrs, Steroids Seller Homepage
    Contact Info
  • +86 15970428662
  • +86 15970428662
  • 3555867920
  • Niky@biolang.cn
  • +86 15970428662
  • +86 15970428662
  • +86 15970428662
  • Biolake 858 High-tech Avenue, Wuhan, Hubei, China
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Item Specifications
  • Appearance:White Powder
  • CAS:19982-08-2
  • Storage:Cool Dry Place
  • Deliver Time:7-10 Days
  • Self Life:2 Years
  • Brand:BIOCAR
Product Description

Product Detail

99% High Quality Original Powder Memantine CAS 19982-08-2 with Safe Delivery

Basic Information

Product name Memantine 
Cas number 19982-08-2
Molecular formula C12H22ClN
Molecular weight  215.76
Appearance white powde
Melting point 153
Boiling point 239.8 at 760 mmHg
Relative density 1.046

What is Memantine?
Memantine hydrochloride is a raw material. It should be prescribed by experienced doctors in the diagnosis and treatment of Alzheimer's dementia and guided by patients. Treatment can only begin when there are caregivers around the patient who regularly supervise the patient's medication. Dementia should be diagnosed in accordance with current diagnostic criteria and guidelines.

Description
Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Treatment should only be continued if beneficial effects are seen. It is taken by mouth.
Memantine was approved for medical use in the United States in 2003. It is available as a generic medication. In 2017, it was the 149th most commonly prescribed medication in the United States, with more than four million prescriptions


Memantine Benefits

Memantine HCl is the HCl form of Memantine. Memantine is a well- known neuroprotective drug used for the treatment of Alzheimer's disease. It is believed to be the first neuroprotective drug that has achieve clinical approval by US FDA as well as European.
The development of Alzheimer's disease involves the misfolded mutant proteins such as β-amyloid peptide (Aβ, particularly Aβ1−42). These misfolded mutant protein can increase the NMDA response and further cause severe excitotoxicity.
Memantine suppresses this process through acting as the antagonist of the N-methyl-d- aspartate-sensitive glutamate receptor (NMDARs).
Memantine is also under investigation as a potential treatment for other kind of neurodegenerative disorders such as HIV-associated dementia, neuropathic pain, glaucoma, depression, Huntington's disease, ALS and movement disorders, among other. 


Medical Use   
Memantine is used to treat moderate-to-severe Alzheimer's disease, especially for people who are intolerant of or have a contraindication to AChE (acetylcholinesterase) inhibitors.One guideline recommends memantine or an AChE inhibitor be considered in people in the early-to-mid stage of dementia.

Memantine has been associated with a modest improvement; with small positive effects on cognition, mood, behavior, and the ability to perform daily activities in moderate-to-severe Alzheimer's disease. There does not appear to be any benefit in mild disease.

Memantine when added to donepezil in those with moderate-to-severe dementia resulted in "limited improvements" in a 2017 review. The UK National Institute of Clinical Excellence (NICE) issued guidance in 2018 recommending consideration of the combination of memantine with donepezil in those with moderate-to-severe dementia. Effects in autism are unclear. Recent scientific journal reports are showing guarded promise with severe obsessive compulsive disorder.


COA

Item

Requirements

Test Results

appearance

White or almost white crystalline powder 

White crystalline powder 

Identification

IR 

Comply 

Related substance 

1-methyladamantane 0.3%

1,3,5 -trimethyladamantane 0.3%

Unknow impuritiy     0.1%

Total impurity 0.5%

0.13%

0.14%

<0.1%

<0.4%

Residue on ignition 

0.1% 

0.06%

Heavy matal 

10ppm 

<10ppm 

Loss on drying 

0.5%

0.29%

Assay

98.5-101.0%

99.13%

Residual

Solvents

Ethyl Acetate: 0.5%

Ethanol: 0.5%

0.08%

0.12%

PH

4.5-5.5 

5.3

Microbial Limits

Max 5*102 aerobes and fungl per 1g 

E. Coli: Negative Salmonella: Negative


Pass 

Size of distributed particles 

Pass 100μ m

Conforms

Conclusion

Meet the requirements 

Our Company
Wuhan Biocar Pharmaceutical Co., Ltd. is a high-tech innovative enterprise specializing in the R & D, production and sales of API and pharmaceutical intermediates (excluding drugs). Our company is based on the optical valley biological city, with the help of Wuhan University Scientific Research Laboratory, making full use of the park policy advantages, focusing on the research and development of biological medicine. Our company always adheres to the business philosophy of "market demand oriented; technology research and development as the core competitiveness; e-commerce as the platform", more accurate, better, faster and more reliable to provide biomedical products for pharmaceutical units, university scientific research institutions, hospital outpatient service, reagent units, distributors in the world.


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