Product Detail

99% High Quality Original Powder Setipiprant CAS 866460-33-5 with Safe Delivery

Basic Information

Description
Setipiprant (INN) (developmental code names ACT-129,968, KYTH-105) is a drug originally developed by Actelion which acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2). It was initially researched as a treatment for allergies and inflammatory disorders, particularly asthma, but despite being well tolerated in clinical trials and showing reasonable efficacy against allergen-induced airway responses in asthmatic patients, it failed to show sufficient advantages over existing drugs and was discontinued from further development in this application.
However, following the discovery in 2012 that the prostaglandin D2 receptor (DP/PGD2) is expressed at high levels in the scalp of men affected by male pattern baldness, the rights to setipiprant were acquired by Kythera with a view to potentially developing this drug as a novel treatment for baldness, with a previously unexploited mechanism of action. While it is too early to tell whether setipiprant will be an effective treatment for this condition, the favorable pharmacokinetics and relative lack of side effects seen in earlier clinical trials mean that fresh clinical trials for this new application can be conducted fairly quickly.
A phase 2A study is underway to evaluate the safety, tolerability, and efficacy of oral setipiprant relative to a placebo and the active comparator, finasteride, in 18 to 41 years old males with androgenetic alopecia.


Application
1. Increase cellular proliferation of outer root sheeth cells.
2. Increase hair diameter and hair density.
3. Increase the percentage of hair in the anagen phase.
4. Exert no negative effect on body hormone levels.
5. Provide equivalent or better net growth than Finasteride.

Type of  Hair Loss

Androgenetic alopecia
 This form of hair loss is also called male pattern baldness.It can  be also occur in women as well

Telogen Effluvium
This form of hair loss causes the person to loose more than 90% of their hair

Alopecia Areata
This condition can affect people as young as 18.It happens when your immune systerm starts attacking your hair follocles

Traction Alopecia
This hair loss condition can affect males or Females.It couses portions of your hair to fall out at the edges.Hairstyles such as pigtails dreadlocks and braids are the cause of this conditon.

Anagen Effluvium
This condition causes shedding during the anagen phase or growth stage.Chemotherapy is the most common cause.

Anti-Hair Loss Solution

Our Company
Wuhan Biocar Pharmaceutical Co., Ltd. is a high-tech innovative enterprise specializing in the R & D, production and sales of API and pharmaceutical intermediates (excluding drugs). Our company is based on the optical valley biological city, with the help of Wuhan University Scientific Research Laboratory, making full use of the park policy advantages, focusing on the research and development of biological medicine. Our company always adheres to the business philosophy of "market demand oriented; technology research and development as the core competitiveness; e-commerce as the platform", more accurate, better, faster and more reliable to provide biomedical products for pharmaceutical units, university scientific research institutions, hospital outpatient service.