Appearance: White Crystalline PowderCAS: 5875-06-9Storage: Cool Dry PlaceSelf Life: 2 YearsDeliver Time: 7-10 DaysBrand: BIOCAR
Product Detail
Factory Supply 99% High Quality Original Powder Proparacaine Hydrochloride CAS 5875-06-9 with Safe Delivery
Basic Information
Product Name | Proparacaine Hydrochloride |
CAS NO: | 5875/6/9 |
Molecular Formular | C16H27ClN2O3 |
EINECS NO | 227-541-7 |
Purity | 99% |
Appearance | powder |
Place of origin | China |
MOQ | 100G |
Description
Proparacaine HCl is a local topical eye anesthetic important for use during and after eye surgery such as laser eye treatments. Anesthesia, local-Proparacaine and tetracaine are indicated to produce local anesthesia of short duration for ophthalmic procedures including measurement of intraocular pressure, removal of foreign bodies and sutures, and conjunctival and corneal scraping in diagnosis and gonioscopy.
Proparacaine hydrochloride and tetracaine are also indicated to produce local anesthesia prior to surgical procedures such as cataract extraction and pterygium excision, usually as an adjunct to locally injected anesthetics.
Ophthalmic solutions used for intraocular procedures should be preservative-free. Preservatives may cause damage to the corneal epithelium if a significant quantity of solutionenters the eye through the incision.
COA
Items | Standards | Results |
Appearance | White to light yellow crystalline powder | Complies |
Identification | It should be Nitrogen base reaction | Complies |
By UV | Complies | |
Should display the reaction of chloride differentiated | Complies | |
Solubility | Should dissolved in water, warm ethanol and methanol, insoluble in ether and benzene, the solution is neutral to litmus | Complies |
Melting Point | 178ºC~185ºC | 180.3~182.1ºC |
Loss on Drying | ≤ 0.50% | 0.14% |
Residue on Ignition | ≤ 0.15% | 0.03% |
Residual Solvents | DMF: ≤880ppm | ND |
Ethanol: ≤5000ppm | ND | |
Acetone: ≤5000ppm | ND | |
Isopropanol: ≤5000ppm | ND | |
Toluene: ≤890ppm | ND | |
Methanol: ≤3000ppm | ND | |
Related Substances | If the impurities are detected, then the total amount of the impurities should be not more than 2.0%. | Complies |
Assay (on the anhydrous basis) | 97.0%~103.0% | 99.67% |
Reference Standard | USP35 Standard | |
Conclusion | The product complied to USP35 standard. | |
Storage | Preserve in tight,light-resistant containers in a cool place |
Usage
1.Polymerization:
It can be polymerized to give polyvinylacetate. With other monomers can be used to prepare copolymerssuch as ethylene-vinyl acetate (EVA), vinylacetate-acrylic acid (VA/AA), polyvinyl chloride acetate (PVCA), and polyvinylpyrrolidone (Vp/Va Copolymer, used in hair gels).Due to the instability of the radical, attempts to control the polymerizationvia most 'living/controlled' radical processes have proved problematic.However, RAFT (or more specifically MADIX)polymerization offers a convenient method of controlling the synthesis of PVAby the addition of a xanthate or a dithiocarbamate chain transfer agent.
2.Other reactions:
Vinyl acetate undergoes many of the reactions anticipated for an alkeneand an ester.Bromineadds to give the dibromide. Hydrogen halides add to give 1-haloethyl acetates,which cannot be generated by other methods because of the non-availability ofthe corresponding halo-alcohols. Acetic acid adds in the presence of palladiumcatalysts to give ethylidene diacetate, CH3CH(OAc)2. Itundergoes transesterification with a variety of carboxylicacids.The alkene also undergoes Diels-Alderand 2+2 cycloadditions.
3.Toxicity evaluation:
On January 31, 2009, the Government of Canada's final assessment concludedthat exposure to vinyl acetate is not considered to be harmful to human health.Thisdecision under the Canadian Environmental Protection Act (CEPA) was based onnew information received during the public comment period, as well as morerecent information from the risk assessment conducted by the European Union.
Application
The medicine Proparacaine Hydrochloride (HCl) is a local anesthetic used to prevent pain during eye exams or eye surgery. It is commonly sold under the brand name Alcaine in the form of liquid eye drops. It may also be used to alleviate pain after laser eye surgery and other treatments to the eyes. This topical ophthalmic anesthetic is also used for short term relief from corneal burns and corneal abrasions.
Related Products
Anesthetic / Pain Killer | |||
Tetracaine Base | 94-24-6 | Prilocaine hydrochloride | 1786-81-8 |
Tetracaine hydrochloride | 136-47-0 | Proparacaine hydrochloride | 5875/6/9 |
Lidocaine hydrochloride | 73-78-9 | Pramoxine hydrochloride | 637-58-1 |
Linocaine Base | 137-58-6 | Procainamide hydrochloride | 614-39-1 |
Benzocaine hydrochloride | 23239-88-5 | Ropivacaine hydrochloride | 98717-15-8 |
Benzocaine Base | 1994/9/7 | Articaine hydrochloride | 23964-57-0 |
Procaine | 59-46-1 | Bupivacaine | 2180-92-9 |
Procaine hydrochloride | 1951/5/8 | Mepivacaine hydrochloride/Carbocaine | 1722-62-9 |
Prilocaine | 721-50-6 | dibucaine hydrochloride | 1961/12/1 |
Our Company
Wuhan Biocar Pharmaceutical Co., Ltd. is a hightech innovative enterprise specializing in the R & D, production and sales of API and pharmaceutical intermediates (excluding drugs). Our company is based on the optical valley biological city, with the help of Wuhan University Scientific Research Laboratory, making full use of the park policy advantages, focusing on the research and development of biological medicine. Our company always adheres to the business philosophy of "market demand oriented; technology research and development as the core competitiveness; e-commerce as the platform", more accurate, better, faster and more reliable to provide biomedical products for pharmaceutical units, university scientific research institutions, hospital outpatient service, reagent units, distributors in the world.