Appearance: White PowderCAS: 43200-80-2Storage: Cool Dry PlaceDeliver Time: 7-10daysShelf Life: 2 YearsBrand: BIOCAR
Product Detail
High Quality Original Powder Zopiclone CAS 43200-80-2 with Best Price
Basic Information
Product name: | Zopiclone,Imovane |
Alias: | 4-Methyl-1-piperazinecarboxylic acid 6 - (5-chloro-2-pyridinyl) -6, 7-dihydro-7-oxo-5H-pyrrolo [3, 4-b] pyrazin-5-yl ester; Imovane |
CAS: | 43200-80-2 |
EINECS: | 256-138-9 |
MF: | C17H17ClN6O3 |
MW: | 388.81 |
Assay: | 99.5% min |
Apperance: | White powder or yellowish powder |
Density: | 1.54 g/cm3 |
Boiling Point: | 580.7 °C at 760 mmHg |
Melting Point: | 178 °C |
Flash Point: | 305 °C |
Storage Temperature: | Keep tightly closed |
Solubility: | DMSO: 2 mg/mL |
Description
Zopiclone (brand names Zimovane and Imovane) is a nonbenzodiazepine hypnotic agent used in the treatment of insomnia. It is a cyclopyrrolone, which increases the normal transmission of the neurotransmitter gamma-Aminobutyric acid in the central nervous system, as benzodiazepines do, but in a different way.
As zopiclone is sedating, it is marketed as a sleeping pill. It works by causing a depression or tranquilization of the central nervous system. After prolonged use, the body can become accustomed to the effects of zopiclone. When the dose is then reduced or the drug is abruptly stopped, withdrawal symptoms may result. These can include a range of symptoms similar to those of benzodiazepine withdrawal. Although withdrawal from therapeutic doses of zopiclone and its isomers do not typically present with convulsions and are therefore not considered life-threatening, patients may experience such significant agitation and/or anxiety that they seek emergency medical attention.
Function
Zopiclone is a tranquilliser drug. It works by causing a depression or tranquillisation of the Central Nervous System. As Zopiclone is sedating it is marketed as a sleeping pill. After regular dampening down of the Central Nervous System the body becomes accustomed to functioning under the influence of Zopiclone.
Zopiclone belongs to the class of medications called sedative-hypnotics. It is used for the short-term and symptomatic relief of sleep disturbances. Zopiclone can help with difficulty falling asleep, frequent wake-ups during the night, or early morning awakenings. Zopiclone should usually not be taken for more than 7 to 10 consecutive days. It should be used only by people for whom disturbed sleep results in problems functioning during the day.
How Does It Work ?
Zopiclone belongs to the class of medications called sedative-hypnotics. It is used for the short-term and symptomatic relief of sleep disturbances. Zopiclone can help with difficulty falling asleep, frequent wake-ups during the night, or early morning awakenings. Zopiclone should usually not be taken for more than 7 to 10 consecutive days. It should be used only by people for whom disturbed sleep results in problems functioning during the day.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Dosage
The usual starting dose is 3.75 mg taken just before bedtime when required to help with difficulty sleeping. The recommended adult dose of zopiclone ranges from 3.75 mg to 7.5 mg. The maximum daily dose is 5 mg for seniors, people with reduced liver or kidney function, and people taking certain medications. This medication may be habit-forming and should be taken exactly as prescribed by your doctor. You should not typically use zopiclone for more than 7 to 10 days in a row.
COA
Contents | Standard | Resuits of analysis |
Appearance | White or yellowish powder | Kind of white powder |
Identification | Comply with the standard | Conforms |
Optical rotation | -0.05~+0.05° | 0.00° |
Appearance of solution | Comply with the standard | Conforms |
Sulphated ash | <0.1% | 0.05% |
2-Propanol | <0.7% | Conforms |
Heavy metals | <20ppm | Conforms |
Individual impurity | <0.3% | 0.09% |
<0.1 Impurity count | <2% | Conforms |
Assay | 98.5~100.5% | 99.64% |
Result : Conforms to USP |