Biocar Pharmaceutical Co.,Ltd. 
Appearance: White PowderCAS: 175591-23-8Storage: Cool Dry PlaceSelf Life: 2 YearsDeliver Time: 7-10 DaysBrand: BIOCAR
Product Detail
Wholesales 99% High Quality Original Powder Tapentadol CAS175591-23-8 with Safe Delivery
Basic Information
| Product Name | Tapentadole |
| Other Name | Nucynta |
| CAS NO | 175591-23-8 |
| Molecular Weight | 257.799 |
| Density | 0.97g/cm3 |
| Boiling Point | 323.5ºC at 760mmHg |
| Molecular Formula | C14H24ClNO |
| Melting Point | 178-194°C |
| Flash Point | 134.2ºC |
What is Chloroquine Phosphate?
Tapentadol, brand names Nucynta among others, is a centrally acting opioid analgesic of the benzenoid class with a dual mode of action as an agonist of the μ-opioid receptor and as a norepinephrine reuptake inhibitor (NRI).[1] Analgesia occurs within 32 minutes of oral administration, and lasts for 4-6 hours.
Description
It is similar to tramadol in its dual mechanism of action; namely, its ability to activate the mu opioid receptor and inhibit the reuptake of norepinephrine. Unlike tramadol, it has only weak effects on the reuptake of serotonin and is a significantly more potent opioid with no known active metabolites. Tapentadol is not a pro-drug and therefore does not rely on metabolism to produce its therapeutic effects; this makes it a useful moderate-potency analgesic option for patients who do not respond adequately to more commonly used opioids due to genetic disposition (poor metabolizers of CYP3A4 and CYP2D6), as well as providing a more consistent dosage-response range among the patient population.Application
Tapentadol is used for the treatment of moderate to severe pain for both acute (following injury, surgery, etc.) and chronic musculoskeletal pain. It is also specifically indicated for controlling the pain of diabetic neuropathy when around-the-clock opioid medication is required. Extended-release formulations of tapentadol are not indicated for use in the management of acute pain.
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